Abstract：It is the characteristic of children constitution that the heart and the liver is often in superabundance，while the lung，the spleen and the kidney is often insufficient. Based on the characteristic，the study classified the nature of childhood enuresis to deficiency and excess，describing its etiology and pathogenesis of Chinese medicine，and analyzing the features of prescription and combination of Sangpiaoxiao powder in the treatment of childhood enuresis from the perspectives of four qi，five flavors and meridian entry.