针刺联合桃红四物汤治疗类风湿关节炎临床研究
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R593.22;R274.9

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Clinical Study on Acupuncture Combined with Taohong Siwu Tang for Rheumatoid Arthritis
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    摘要:

    目的:观察针刺联合桃红四物汤治疗类风湿关节炎(RA) 的临床疗效。方法:将96 例RA 患者按随机数字表法为对照组和观察组各48 例。对照组给予甲氨蝶呤片联合硫酸羟氯喹片治疗,观察组在对照组基础上加用针刺及桃红四物汤治疗,2 组均治疗3 个月。比较2 组治疗前后关节疼痛程度及睡眠质量,分别采用视觉模拟评分法(VAS) 及匹兹堡睡眠质量指数(PSQI) 评价;观察2 组治疗前后类风湿因子(RF)、超敏C-反应蛋白(hs-CRP)、血沉(ESR) 水平及症状积分的变化;比较2 组临床疗效。结果:治疗后,2 组VAS、PSQI 评分均较治疗前降低(P<0.05),观察组VAS、PSQI 评分均低于对照组(P<0.05)。治疗后,2 组血清RF、hs-CRP 及ESR 水平均较治疗前降低,差异均有统计学意义(P<0.05);观察组RF、hs-CRP及ESR 水平均低于对照组,但差异均无统计学意义(P>0.05)。治疗后,2 组晨僵、关节屈伸不利、关节疼痛、关节肿胀积分及症状总积分均较治疗前降低(P<0.05),观察组晨僵、关节屈伸不利、关节疼痛、关节肿胀积分及症状总积分均低于对照组(P<0.05)。观察组总有效率为83.3%,高于对照组的64.6%,差异有统计学意义(P<0.05)。结论:针刺联合桃红四物汤治疗RA,可有效缓解患者关节疼痛、肿胀等症状,改善其睡眠状况,提高临床疗效。

    Abstract:

    Abstract: Objective: To observe the clinical effect of acupuncture combined with Taohong Siwu tang for rheumatoid arthritis(RA). Methods: A total of 96 cases of RA patients were divided into the control group and the observation group according to the random number table method,48 cases in each group. The control group was treated with methotrexate tablets combined with hydroxychloroquine sulfate tablets, and the observation group was additionally treated with acupuncture and Taohong Siwu tang based on the treatment of the control group. Both groups were treated for three months. Before and after treatment, the degree of the joint pain and sleep quality in the two groups were evaluated by Visual Analogue Scale(VAS) and Pittsburgh Sleep Quality Index(PSQI) respectively;the changes in the levels of rheumatoid factors (RF), hypersensitive C- reactive protein(hs- CRP) and erythrocyte sedimentation rate(ESR) and symptom scores in the two groups were observed. The clinical effect in the two groups was compared. Results:After treatment,the scores of VAS and PSQI in the two groups were decreased when compared with those before treatment(P<0.05), and the scores in the observation group were lower than those in the control group(P<0.05). After treatment,the levels of RF,hs-CRP and ESR in serum in the two groups were decreased when compared with those before treatment,differences being significant(P< 0.05);the above levels in the observation group were all lower than those in the control group,but there was no significance in the difference(P>0.05). After treatment, the scores of morning stiffness, retarded flexion and extension of the joints, joint pain,joint swelling and the total scores in the two groups were decreased when compared with those before treatment (P<0.05), and the above scores in the observation group were lower than those in the control group(P<0.05). The total effective rate was 83.3% in the observation group, higher than that of 64.6% in the control group, the difference being significant(P<0.05). Conclusion:Acupuncture combined with Taohong Siwu tang for RA can effectively relieve the symptoms such as joint pain and swelling and improve the sleep status and clinical effect.

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方立,黄芳.针刺联合桃红四物汤治疗类风湿关节炎临床研究[J].新中医,2020,52(21):110-113

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  • 在线发布日期: 2020-11-05
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