pregnancy. Methods：A total of 93 cases of patients were randomly divided into the control group and the observation group according to the prospective method， 46 and 47 cases in each group respectively. The control group was treated with compound ferrous sulfate and folic acid tablets， and the observation group was treated with Jianpi Shengxue tablets. The hematological indexes，clinical effect and adverse reactions in the two groups were compared. Results：Before treatment， there was no significant difference being found in the comparison of hematological indexes between the two groups(P＞0.05). After treatment， the hematological indexes in the two groups were improved； the improvement in the observation group was better than that in the control group， the difference being significant(P＜0.05). The effective rate was 95.74% in the observation group， significantly higher than that of 80.43% in the control group， the difference being significant(P＜0.05). The incidence of adverse reactions was 4.26% in the observation group， lower than that of 13.04% in the control group， there being no significance in the difference(P＞0.05). After reducing the medicine dose， the adverse reactions in the two groups disappeared. Conclusion：The application of Jianpi Shengxue tablets has significant effect in treating iron deficiency anemia during pregnancy，which can effectively improve the anemia in patients with few adverse reactions.