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| 认知行为疗法、中医情志护理配合重复经颅磁刺激干预精神分裂症临床研究 |
| 陈德沈,沙建敏,吕双燕,林小东,林崇光,姜德国,郑维芳,马红 |
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| (1. 温州市第七人民医院，浙江温州325000;2. 温州医科大学附属第二医院，浙江温州325000) |
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| 摘要: |
| 目的：观察认知行为疗法、中医情志护理配合重复经颅磁刺激（rTMS） 干预精神分裂症的临床疗效。方法：选取120 例精神分裂症患者，按随机数字表法分为观察组和对照组各60 例。观察组实施认知行为疗法、中医情志护理配合rTMS 治疗，对照组实施认知行为疗法、情志护理及伪rTMS 治疗，2 组均干预4 周。比较2 组临床疗效及治疗前后阳性与阴性症状量表（PANSS）、临床总体印象量表（CGI）、精神分裂症认知功能简明成套测评量表（BACS） 及个人与社会功能量表（PSP） 评分。结果： 观察组总有效率96.67%， 对照组总有效率83.33%， 2 组比较， 差异有统计学意义（P＜0.05）。治疗后， 2 组PANSS、CGI 评分均较治疗前降低（P＜0.05），观察组PANSS、CGI 评分均低于对照组（P＜0.05）。治疗后，2 组BACS、PSP 评分均较治疗前升高（P＜0.05），观察组BACS、PSP 评分均高于对照组（P＜0.05）。结论：认知行为疗法、中医情志护理配合rTMS 干预精神分裂症，可有效缓解患者的阳性、阴性症状，改善其认知功能和社会功能。 |
| 关键词: 精神分裂症 重复经颅磁刺激 认知行为疗法 中医情志护理 阳性与阴性症状量表 认知功能 社会功能 |
| DOI： |
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| 基金项目:温州市2017公益性科技计划项目（Y20170362） |
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| Clinical Study on Cognitive Behavioral Therapy and Emotional Nursing of ChineseMedicine Combined with Repetitive Transcranial Magnetic Stimulation InterveningSchizophrenia |
| CHEN Deshen,SHA Jianmin,LYU Shuangyan,LIN Xiaodong,LIN Chongguang,JIANG Deguo,ZHENG Weifang,MA Hong |
| (单篇PDF全文查阅请上中国知网下载阅读（中国知网电子版刊出时间：纸刊刊出日期一个月左右）) |
| Abstract: |
| Abstract： Objective： To observe the clinical effect of cognitive behavioral therapy and emotional nursing of Chinese
medicine combined with repetitive transcranial magnetic stimulation(rTMS) intervening schizophrenia. Methods：A total of 120
cases of patients with schizophrenia were divided into the observation group and the control group according to the random
number table method， 60 cases in each group. The observation group was treated with cognitive behavioral therapy，
emotional nursing of Chinese medicine combined with rTMS， and the control group was treated with cognitive behavioral
therapy，emotional nursing and pseudo rTMS. Both groups were intervened for four weeks. The clinical effect as well as the
scores of Positive and Negative Symptoms Scale(PANSS)， Clinical Global Impression Scale(CGI)， Brief Assessment of
Cognition in Schizophrenia(BACS) and Personal and Social Performance Scale(PSP) before and after treatment in the two
groups were compared. Results： The total effective rate was 96.67% in the observation group and 83.33% in the control
group， the difference being significant(P＜0.05). After treatment， the scores of PANSS and CGI in the two groups were
decreased when compared with those before treatment(P＜0.05)，and the scores in the observation group were lower than
those in the control group(P＜0.05). After treatment，the scores of BACS and PSP in the two groups were increased when
compared with those before treatment(P＜0.05)， and the scores in the observation group were higher than those in the
control group(P＜0.05). Conclusion： Cognitive behavioral therapy， emotional nursing of Chinese medicine combined with
rTMS intervening schizophrenia can effectively relieve the positive and negative symptoms of patients， and improve their
cognitive and social functions. |
| Key words: Keywords： Schizophrenia Repetitive transcranial magnetic stimulation Cognitive behavioral therapy Emotional
nursing of Chinese medicine Positive and Negative Symptoms Scale Cognitive function Social function |
