中药穴位贴敷辅助治疗慢性阻塞性肺疾病急性加重期伴呼吸衰竭临床研究
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R563.3;R563.8

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Clinical Study on Point Application with Chinese Herbal Medicine for Acute Exacerba⁃ tion of Chronic Obstructive Pulmonary Disease Complicated with Respiratory Failure
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    摘要:

    目的:观察中药穴位贴敷辅助治疗慢性阻塞性肺疾病急性加重期(AECOPD) 伴呼吸衰竭的效果。方法:将108例痰热壅肺证患者随机分为观察组和对照组各54例。2组均给予补充水、电解质、营养等对症支持治疗,氧疗,抗感染治疗和无创通气治疗,并采用相应的护理措施。观察组加予中药穴位贴敷。2组疗程均为7 d。治疗前后评价呼吸困难严重程度,检测肺功能[第1秒用力呼气容积(FEV1) 和第1秒用力呼气容积占预计值百分比(FEV1%)]、动脉血气分析[血氧分压(PaO2)、二氧化碳分压(PaCO2)、血氧饱和度(SaO2)] 和评定主要症状评分。结果:经过7 d的治疗,2组患者的呼吸困难程度均较治疗前减轻(P<0.05),观察组呼吸困难程度轻于对照组(P<0.05)。2组PaO2、SaO2均较治疗前升高(P<0.01),PaCO2均较治疗前下降(P<0.01)。观察组PaO2、SaO2均高于对照组(P<0.05),PaCO2低于对照组(P<0.05)。2组FEV1和FEV1%均较治疗前升高(P<0.01),观察组FEV1和FEV1%均高于对照组(P<0.05)。2 组咳嗽、咯痰、喘息、气短评分均较治疗前下降(P<0.01),观察组咳嗽、咯痰、喘息、气短评分均低于对照组(P<0.01)。结论:采用中药穴位贴敷辅助干预AECOPD合并呼吸衰竭患者,可进一步减轻呼吸困难程度和缓解临床症状,提高患者的肺功能,控制呼吸衰竭。

    Abstract:

    Abstract:Objective:To observe the effect of point application with Chinese herbal medicine for acute exacerbation of chronic obstructive pulmonary disease(AECOPD) complicated with respiratory failure. Methods: A total of 108 cases of patients with phlegm-heat obstructing the lung syndrome were randomly divided into the observation group and the control group, 54 cases in each group. Both groups were treated with symptomatic treatment including water, electrolytes and nutrition,oxygen therapy,anti- infection treatment,noninvasive ventilation,as well as corresponding nursing measures. The observation group was additionally treated with point application with Chinese herbal medicine. Both groups were treated for seven days. Before and after treatment, the severity of dyspnea was evaluated; the lung function including forced expiratory volume in one second(FEV1) and percentage of predicted value of FEV1(FEV1% ), as well as arterial blood gas analysis including partial pressure of oxygen(PaO2), partial pressure of carbon dioxide(PaCO2) and oxygen saturation(SaO2) were detected;the main symptom scores were assessed. Results:After treatment for seven days,the severity of dyspnea in the two groups was relieved(P<0.05),and the severity in the observation group was lighter than that in the control group (P<0.05). The PaO2 and SaO2 in the two groups were increased when compared with those before treatment(P<0.01),and PaCO2 was decreased(P<0.01). The PaO2 and SaO2 in the observation group were higher than those in the control group(P<0.05),and PaCO2 was lower(P<0.05). The FEV1 and FEV1% in the two groups were increased when compared with those before treatment(P<0.01),and the above indexes in the observation group were higher than those in the control group(P<0.05). The scores of cough, expectoration, wheezing and shortness of breath in the two groups were decreased when compared with those before treatment(P<0.01),and the above scores in the observation group were lower than those in the control group(P<0.01). Conclusion: Point application with Chinese herbal medicine in intervening patients with AECOPD complicated with respiratory failure can further relieve the severity of dyspnea and clinical symptoms, improve their lung function and control respiratory failure.

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李安慈.中药穴位贴敷辅助治疗慢性阻塞性肺疾病急性加重期伴呼吸衰竭临床研究[J].新中医,2020,52(11):114-117

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  • 在线发布日期: 2020-06-04
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