香砂六君子汤治疗老年脾胃虚弱型消化性溃疡临床研究
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Clinical Study on Xiangsha Liujunzi Tang for Peptic Ulcer of Spleen-Stomach Deficiency Type in Senile Patients
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    摘要:

    目的:观察香砂六君子汤治疗老年脾胃虚弱型消化性溃疡的临床疗效。方法:选择老年脾胃虚弱型消化性溃疡患者138 例,按随机数字表法分为观察组和对照组各 69 例。对照组给予常规西药治疗,观察组在对照组基础上联合香砂六君子汤治疗。比较 2 组临床疗效,记录 2 组临床症状恢复时间、幽门螺杆菌 (Hp) 转阴率及不良反应。结果:观察组总有效率为95.65%,高于对照组 81.16%,差异有统计学意义 (P<0.05)。观察组嗳气、反酸、上腹烧灼感及腹痛的恢复时间均低于对照组,差异有统计学意义(P<0.05)。治疗后,2 组 Hp 阳性率均有所下降,Hp 转阴率均有所提升,且观察组 Hp 阳性率低于对照组,Hp 转阴率高于对照组,差异均有统计学意义(P<0.05)。观察组不良反应发生率为 5.80%,低于对照组 14.49%,差异有统计学意义(P<0.05)。结论:香砂六君子汤可有效治疗老年脾胃虚弱型消化性溃疡,降低 Hp 阳性率,缓解临床症状。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Xiangsha Liujunzi tang for peptic ulcer of spleen- stomach deficiency type in senile patients. Methods: A total of 138 cases of senile patients with peptic ulcer of spleen- stomach deficiency type were selected and divided into the observation group and the control group according to the random number table method,69 cases in each group. The control group was treated with routine western medicine,and the observation group was additionally treated with Xiangsha Liujunzi tang. The clinical effect was compared between the two groups. The recovery time of clinical symptoms,the negative rate of helicobacter pylori(Hp),and adverse reactions were recorded in the two groups. Results:The total clinical effective rate was 95.65% in the observation group,higher than that of 81.16% in the control group,the difference being significant(P<0.05). The recovery time of belching,acid regurgitation,burning sensation in upper abdomen and abdominal pain in the observation group was shorter than that in the control group,the difference being significant(P<0.05). After treatment, the positive rates of Hp in the two groups were slightly decreased, and the negative rate were slightly increased;the positive rate of Hp in the observation group was lower than that in the control group, and the negative rate was higher than that in the control group, the difference being significant(P<0.05). The incidence of adverse reactions was 5.80% in the observation group,lower than that of 14.49% in the control group,the difference being significant(P<0.05). Conclusion: Xiangsha Liujunzi tang is an effective treatment for senile patients with peptic ulcer of spleen-stomach deficiency type,which can decrease the positive rate of Hp and relieve clinical symptoms.

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周密群.香砂六君子汤治疗老年脾胃虚弱型消化性溃疡临床研究[J].新中医,2020,52(22):43-46

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  • 在线发布日期: 2020-11-27
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