四逆汤对脓毒血症休克患者血压变异性的影响
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R459.7

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Clinical Observation on Effect of Sini Tang on Blood Pressure Variability of Patients with Septic Shock
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    摘要:

    目的:观察四逆汤对脓毒血症休克患者血压变异性的影响。方法:选取本院收治的40例脓毒血症患者,按照随机数字表法分为对照组和观察组各20例。对照组进行常规抢救,观察组在对照组基础上加服四逆汤。观察2组治疗前后血压水平及血压变异性的变化。结果:治疗前,2组收缩压(SBP) 及舒张压(DBP)比较,差异均无统计学意义(P>0.05)。2组首次治疗3 h、6 h、9 h,SBP及DBP均较治疗前升高(P<0.05)。首次治疗3 h,观察组SBP和DBP均高于对照组(P<0.05)。首次治疗6 h,观察组SBP高于对照组(P<0.05);2组DBP比较,差异无统计学意义(P>0.05)。首次治疗9 h,2组SBP及DBP比较,差异均无统计学意义(P>0.05)。治疗5天后,观察组白天SBP、DBP标准差,夜间SBP、DBP标准差,白天SBP、DBP变异系数,夜间SBP、DBP变异系数均低于对照组(P<0.05)。2组血压晨峰比较,差异无统计学意义(P>0.05)。结论:四逆汤可加快脓毒血症休克患者血压回升,有效改善血压变异性。

    Abstract:

    Objective:To observe the effect of Sini tang on blood pressure variability of patients with septic shock.Methods:Selected 40 cases of patients with septic shock who were admitted to our hospital,and divided them into the control group and the observation group according to the random number table method,20 cases in each group.The control group received conventional rescue,while the observation group additionally received Sini tang based on the treatment of the control group.Observed changes in blood pressure and blood pressure variability before and after treatment in both groups.Results:Before treatment, there was no significant difference being found in the comparisons of systolic blood pressure(SBP)and diastolic blood pressure(DBP)between the two groups(P>0.05).At the 3rd,6th,and 9thhours after treatment,the SBP and DBP in the two groups were increased when compared with those before treatment(P<0.05).At the 3rdhour after treatment,the SBP and DBP in the observation group were higher than those in the control group(P<0.05).At the 6thhour after treatment,the SBP in the observation group was higher than that in the control group(P<0.05);there was no significant difference being found in the comparison of DBP between the two groups(P>0.05).At the 9thhour after treatment,there was no significant difference being found in the comparisons of SBP and DBP between the two groups(P>0.05).After five-day treatment,the standard deviation of SBP and DBP at daytime,the standard deviation of SBP and DBP at night,the variation coefficient of SBP and DBP at daytime,and the variation coefficient of SBP and DBP at night in the observation group were all lower than those in the control group(P<0.05).There was no significant difference being found in the comparison of early morning blood pressure surge between the two groups(P>0.05).Conclusion:Sini tang can accelerate the blood pressure rise of patients with septic shock and effectively improve the blood pressure variability.

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汤玲玲.四逆汤对脓毒血症休克患者血压变异性的影响[J].新中医,2018,50(12):181-183

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  • 在线发布日期: 2018-12-09
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