中西医结合治疗慢性鼻炎近远期疗效观察
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R765.21

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Observation of Short-Term and Long-Term Effect of Integrated Chinese and Western Medicine Therapy for Chronic Rhinitis
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    摘要:

    目的:观察中西医结合治疗慢性鼻炎的近、远期临床疗效。方法:将本院耳鼻喉科收治的150例慢性鼻炎患者随机分为2组各75例。对照组予布地奈德喷鼻剂喷鼻及口服克拉霉素治疗;在对照组治疗方案的基础上予鼻炎方口服治疗,并配合穴位按摩,总疗程均为4周。根据临床症状好转情况评价近、远期临床疗效,并于治疗前后采用鼻阻力测量仪测量鼻阻力,记录2组患者治疗期间不良反应发生情况。结果:近期总有效率观察组65.33%,对照组61.33%,2组比较,差异无统计学意义(P>0.05)。远期总有效率观察组86.67%,对照组70.67%,2组比较,差异有统计学意义(P<0.05)。与近期疗效比较,对照组总有效率有所上调,差异无统计学意义(P>0.05);观察组远期疗效较近期疗效提高,差异有统计学意义(P<0.05)。治疗后,2组鼻阻力水平均明显下调,差异均有统计学意义(P<0.05),与对照组比较,观察组鼻阻力水平下降更加明显,差异有统计学意义(P<0.05)。2组患者安全性及不良反应发生率比较,差异无统计学意义(P>0.05)。结论:中西医结合治疗慢性鼻炎能有效缓解鼻塞、流涕等临床症状及体征,改善患者鼻通气,临床疗效明显,且具有一定的安全性。

    Abstract:

    Objective:To observe the short-term and long-term clinical effect of integrated Chinese and western medicine therapy for chronic rhinitis.Methods:Divided 150 cases of patients with chronic rhinitis in department of otolaryngology in Xinyang Third People’s Hospital into two groups randomly,75 cases in each group.Both groups receivedbudesonide nasal spray and clarithromycin for treatment,while the observation group additionally received rhinitis prescription by oral administration and point massage.The overall treatment for both groups lasted for 4 weeks.The short-term and long-term clinical effect of both groups was evaluated according to improvements of clinical symptoms.Nasal resistance of patients before and after treatment were measured by nasal resistance instrument.Adverse reaction of patients in both groups during the treatment were recorded.Results:The short-term total effective rate was 65.33%in the observation group and 61.33%in the control group,there being no significance in the difference(P>0.05).The long-term total effective rate was 86.67%in the observation group and 70.67%in the control group,the difference being significant(P<0.05).Compared with the short-term curative effect,the total effective rate in the control group was increased,there being no significance in the difference(P>0.05);long-term curative effect in the observation group was better than the short-term curative effect,the difference being significant(P < 0.05).After treatment,nasal resistance levels in both groups were decreased significantly,differences being significant(P<0.05).Nasal resistance levels in the observation group were decreased more significantly than those in the control group,the difference being significant(P<0.05).No significant difference was found in the comparison of safety and the incidence rate of adverse reaction of patients between the two groups(P>0.05).Conclusion:Integrated Chinese and western medicine therapy for chronic rhinitis can effectively relief clinical symptoms and signs such as nasal obstruction and nasal discharge as wellas improve nasalventilation of patients,which has significant clinicaleffect and safety.

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刘联合.中西医结合治疗慢性鼻炎近远期疗效观察[J].新中医,2017,49(12):107-109

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  • 在线发布日期: 2017-12-02
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